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Support your body's need to grow and stay strong.
5 Salts
Unlike most calcium products that rely on just one or two basic forms, this advanced blend features five distinct calcium salts, each selected for their superior bioavailability and complementary health benefits.
375mg
of calcium in one serving.
Calcium
Calcium is essential for building and maintaining strong bones. Isotonix Calcium Plus provides the body with an optimal blend of calcium, vitamin D3, manganese, magnesium and vitamin C in an efficient isotonic solution that is readily absorbed by the body. Isotonic supplements bear chemical resemblance to your own tears and plasma, so your body absorbs the nutrients rapidly and more effectively.
Product Classification
Gluten-Free
Vegetarian
Isotonic
No Detectable GMO
Good Manufacturing Practices
Key Ingredients & Benefits
Calcium
Supports bones and teeth health
Supports normal muscle use and nerve health
Vitamin D3 (Cholecalciferol)
Promotes the absorption of calcium
Manganese
Supports the normal formation of connective tissue and bones
Supports calcium absorption
Magnesium
Supports the body’s ability to build healthy bones and teeth
How to Take for Maximum Absorption
Pour 1 small capful (3.3 g) of Isotonix powder into a cup.
Add 60 ml of water for each capful and mix.
Best taken twice daily – 1 capful in the morning and 1 capful in the evening. For maximum absorption, take Isotonix powder drink on an empty stomach.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
Why should I take calcium?
Practically no one ingests enough calcium in their daily diet, so calcium is one of the nutrients that is highly recommended in terms of supplementation. Besides being helpful in supporting and maintaining bone integrity, calcium serves a dynamic role as a mineral. It is very important in the activity of many bodily enzymes. It is important for athletes in maintaining proper fluid balance as well as aiding in the action of skeletal and muscle contraction. In addition, calcium may be helpful in preventing the incidence of colon cancer. Canadians are being urged to increase their intake of fresh fruits and vegetables to get the required minerals, however for those who do not typically have the best diets it is important to make sure that one is getting enough of this crucial mineral.
How much calcium should I take?
The National Academy of Sciences has established guidelines for calcium that are 25 to 50 percent higher than previous recommendations. For ages 20 to 50, calcium consumption is recommended to be at least 1,000 mg daily; for adults over age 51, the recommendation is 1,200 mg daily. The most common supplemental amount for adults is 800 to 1,000 mg per day. Some physicians recommend 1,000 milligrams of supplement calcium daily for postmenopausal women taking estrogen replacement therapy (ERT) and 1,500 milligrams daily for postmenopausal women not taking ERT. An intake of 1,200 milligrams daily appears to be adequate for both groups.
I am not an elderly woman. Why should I supplement with calcium?
Calcium plays a huge role in many major regulatory bodily processes with implications that extend far beyond the age factor. Other than elderly women who may be susceptible to bone loss, younger women, pregnant and lactating women, growing children and those with high blood pressure are suitable candidates for calcium supplementation. Younger women need more calcium to build up the strength of their bones around the ages of 20 and up. It is safe to say that an ounce of prevention is worth a pound of cure. Pregnant and lactating women need extra calcium, at least 1200 mg /day to foster the healthy growth of new cells and of breast milk. Finally, those with high blood pressure have been found to have low levels of calcium intake and further studies have confirmed the positive impact of calcium supplementation on heart health. Of course, calcium has been most widely touted as a preventative of osteoporosis. Because many people are uneducated about the far-reaching necessity and benefit of calcium, the drive to add a supplement to one's diet is floundering. Further, it has been found that many younger and middle-aged women who should be ingesting greater amounts of calcium in both diet and supplementation, are the ones who actually ingest the least. The mindset that milk products are fattening has contributed to a lack of quality calcium intake. Women in general who have a vested interest in their health should make moves to begin calcium supplementation. Moreover, suppose you are predisposed to osteoporosis and are even feeling a few of the signs of it, including headache and a decrease in height; while calcium supplementation is one of the key ingredients to preventing and even fighting ongoing osteoporosis, there are a few other important factors that must be taken into account. Many other things can also play a role in causing osteoporosis. Some of these are seemingly normal lifestyle factors including smoking, lack of exercise, low levels of magnesium, zinc, vitamin B6, vitamin K, and B12, a high alcohol intake and altered vitamin D metabolism. To fight and/or prevent osteoporosis requires a focus of your attention on these aforementioned variables as well as steadily supplementing your diet with a quality calcium supplement such as Isotonix® Calcium formula. So, in turn, if you know that you are inherently averse to working out or that you like the occasional smoke after work, your need for a good calcium supplement increases tremendously regardless of age.
Research Scope
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- Allender PS, Cutler JA, Follman D, et al. Dietary calcium and blood pressure: meta—analysis of randomized clinical trials. Ann Intern Med. 1996; 124:825-831.
- Altura BM, Altura BT. Role of magnesium and calcium in alcohol-induced hypertension and strokes as probed by in vivo television microscopy, digital image microscopy, optical spectroscopy, 31P-NMR, spectroscopy and a unique magnesium ion-selective electrode.
- Alcohol Clin Exp Res. 1994; 18:1057-1068.
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- Britton J, Pavord I, Richards K, et al. Dietary magnesium, lung function, wheezing, and airway hyper-reactivity in a random adult population sample. Lancet. 1994; 344:357-362.
- Buckley LM, Leib ES, Cartularo KS, et al. Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. Ann Intern Med. 1996; 125:961-968.
- Casscells W. Magnesium and myocardial infarction. Lancet. 1994; 343:807-809.
- Christiansen CW, Rieder MA, Silverstein EL, Gencheff NE. Magnesium sulfate reduces myocardial infarct size when administered before but not after coronary reperfusion in a canine model. Circulation. 1995; 92:2617-2621.
- Christin Marandino, Vegetarian Times, August 1998 Curhan GC, Willett WC, Speizer FE, et al. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk of kidney stones in women. Ann Intern Med. 1997; 126:497-504.
- Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density on men and women 65 years of age and older. N Engl J Med. 1997; 337:670-676.
- de Lourdes Lima M, Cruz T, Carreiro Pousada J, et al. The effect of magnesium supplementation in increasing doses on the control of type 2 diabetes. Diabetes Care. 1998; 21:682-686.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
- Elisaf M, Merkouropoulos M, Tsianos EV. Siamopoulos KC. Pathogenetic mechanisms of hypomagnesemia in alcoholic patients. J Trace Elem Med Biol. 1995; 9:210-214.
- Facchinetti F, Borella P, Sances G, et al. Oral magnesium successfully relieves premenstrual mood changes. Obstet Gynecol. 1991; 78:177-181.
- Garland CF, Garland FC, Gorham ED. Calcium and vitamin D. Their potential roles in colon and breast cancer prevention. Ann NY Acad Sci. 1999; 889:107-119.
- Gong H, Amemiya T. Optic nerve changes in manganese-deficient rats. Exp Eye Res. 1999; 68:313-320.
- Gullestad L, Dolva LO, Soyland E, et al. Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics. Alcohol Clin Exp Res. 1992; 16:986- 990.
- Health & Medicine. (Statistical Data Included) American Fitness, July, 1999 Tannen RL.
- Effects of potassium on blood pressure control. Ann Intern Med. 1983; 98(part 2):773-780.
- Heaney RP. Calcium, dairy products and osteoporosis. J Am Coll Nutr. 2000; 19(2 Suppl):83S-99S.
- Hussain S, Ali SF. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neuroscience Letters. 1999; 261:21-24.
- ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulfate in 58,050 patients with suspected acute myocardial infarction. Lancet.1995; 345:669-685.
- Jorde R, Sundsfjord J, Haug E, et al. Relation between low calcium intake, parathyroid hormone, and blood pressure. Hypertension 2000;35:1154-1159.
- Kao WHL, Folsom AR, Nieto J, et al. Serum and dietary magnesium and the risk for type 2 diabetes mellitus (editorial). Arch. Int Med. 1999; 159:2151-2159.
- Keen CL, Ensunsa JL, Watson MH, et al. Nutritional aspects of manganese from experimental studies. Neurotoxicol. 1999; 20:213-223.
- Krieger D, Krieger S, Jansen O, et al. Manganese and chronic hepatic encephalopathy.Lancet. 1995; 346:270-274.
- Lim R, Herzog WR. Magnesium for cardiac patients: is it a valuable treatment supplement? Contemp Int Med. 1998; 10:6-9.
- Lipkin M, Newmark H. Effect of added dietary calcium on colonic epithelial-cell proliferation in subjects at high risk for familial colonic cancer. N Engl J Med. 1985; 313:1381-1384.
- Lucas MJ, Leveno KJ, Cunningham FG. A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. N Engl J Med. 1995; 333:201-205.
- Martini LA. Magnesium supplementation and bone turnover. Nutr Rev. 1999; 57:227-229.
- Mauskop A, Altura BM. Role of magnesium in the pathogenesis and treatment of migraines. Clin Neurosci. 1998; 5:24-27.
- Nielsen FH. Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-69.
- Nielsen FH. Ultratrace minerals. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins; 1999:283-303.
- Oginni LM, Sharp CA, Worsfold M, et al. Healing of rickets after calcium supplementation.Lancet. 1999; 353:296-297.
- Orchard TJ. Magnesium and type 2 diabetes mellitus (editorial). Arch Int Med. 1999;159:2119-2120.
- Paolisso G, Sgamabato S, Pizza G, et al. Improved insulin response and action by chronic magnesium administration in aged NIDDM. Diabetes Care. 1989; 12:265-269.
- Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia. 1996; 16:257-263.
- Recker RR. Calcium absorption and achlorhydria. N Engl J Med. 1985; 313:70-73. Reid IR, Ames RW, Evans MC, et al. Effect of calcium supplementation on bone loss in postmenopausal women. N Engl J Med. 1993; 328:460-464.
- Rivlin RS. Magnesium deficiency and alcohol intake: mechanisms, clinical significance and possible relation to cancer development (a review). J Am Coll Nutr. 1994; 13:416-423.
- Roberts JM. Magnesium for preeclampsia and eclampsia. N Engl J Med. 1995; 333:250-251.
- Roffe C, Fletcher S, Woods KL. Investigation of the effects of intravenous magnesium sulphate on cardiac rhythm in acute myocardial infarction. Br Heart J. 1994; 71:141-145.
- Saris N-EL, Mervaala E, Karppanen H, et al. Magnesium. An update on physiological, clinical and analytical aspects (review). Clinica Chimica Acta. 2000; 294:1-26.
- Shils ME. Magnesium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in
- Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:169-192.
- Singh MA. Combined exercise and dietary intervention to optimize body composition in aging. Ann N Y Acad Sci. 1998 Nov 20;854:378-93.
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000; 283:2822-2825.
- Sojka JE. Magnesium supplementation and osteoporosis. Nutr Rev. 1995; 53:71-80.
- Strause L, Saltman P, Glowacki J. The effect of deficiencies of manganese and copper on osteo-induction and on resorption of bone particles in rats. Calcif Tissue Int. 1987; 41:145-150.
- Strause L, Saltman P, Smith KT, et al. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. J Nutr. 1994; 124:1060-1064.
- Talbot JR, Guardo P, Seccia S, et al. Calcium bioavailability and parathyroid hormone acute changes after oral intake of dairy and nondairy products in healthy volunteers. Osteoporosis Int. 1999; 10:137-142.
- Tobian L. Salt and hypertension. Lessons from animal models that relate to human hypertension. Hypertension. 1991; 17:152-158.
- Tosiello L. Hypomagnesemia and diabetes mellitus. A review of clinical implications. Arch Intern Med. 1998; 156:1143-1148.
- Wargovich MJ, Eng VWS, Newmark HL. Calcium inhibits the damaging and compensatory proliferative effects of fatty acids on mouse colon epithelium. Cancer Lett. 1984; 23:253-258.
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Reviews
Customer Rating
4.7 out of 5 star rating.
(89 reviews)
would recommend this product.
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This is the best Calcium supplement I have used. I sued to have leg cramps at night when sleeping. but after taking it , the cramps gradually decreased, and now they never happen anymore.
Response from Customer Service on 04/29/2026
Thank you so much for your wonderful review! We're delighted to hear that Isotonix® Calcium Plus has been the best calcium supplement for you and that you've had such a positive experience with it. Your feedback means a lot to us, please let us know if there is anything we can assist you with in the future. Thank you for being a valued member of our community!
我最喜欢的等渗钙
by Anonymous
on 04/18/2026
非常喜欢的一款产品,用了二十多年
等滲钙, 容易吸收,使用
by Anonymous
on 02/09/2026
老人、孩子也喜欢喝, 补钙效果杠杠好
Response from Customer Service on 02/09/2026
非常感谢您的精彩评价!我们很高兴得知您全家老少都喜欢 Isotonix® Calcium Plus,并且觉得它使用方便。您的反馈对我们意义重大——感谢您选择我们的产品,也感谢您成为我们社区的重要成员!
Thank you so much for your wonderful review! We're delighted to hear that Isotonix® Calcium Plus is enjoyed by all ages in your family and that you find it easy to use. Your feedback means a lot to us—thank you for choosing our product and for being a valued part of our community!
Isotonix calcium Plus
by HillaryL
Shop Consultant
on 02/07/2026
I love the taste of Isotonix calcium Plus very much!
It smell like oranges juice!
And Isotonix calcium Plus contains five different types of calcium that our body needed also another vitamins too……
Response from Customer Service on 02/09/2026
Thank you so much for your wonderful review! We’re delighted to hear that you love the taste of Isotonix® Calcium Plus and enjoy its orange juice aroma. It’s great to know you appreciate the variety of calcium sources and additional vitamins it provides. Your feedback truly means a lot to us—thank you for being a valued member of our community!
Milligram
by Anonymous
on 01/13/2025
Hi, can you confirm that one capful is 1,000 mg? I have taken this Calcium and loved it.
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