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Beyond Energy
All 8
essential B vitamins. Each B vitamin plays a critical role in supporting brain health, red energy and nervous system
10X
P5P, or B6 is 10 times more bioavailable than standard pyridoxine hydrochloride.
ZERO
No fillers, binders, artificial colours or flavours.

Vitamin B complex: The Powerhouse of Energy
Choosing a complete B-Complex supplement—containing all eight essential B vitamins—ensures a balanced and effective approach to support energy production, brain function, and cellular metabolism. B vitamins work synergistically. Taking them together enhances their individual benefits while promoting optimal absorption and avoiding nutrient imbalances that can occur with isolated supplementation.

Product Classification

Gluten-Free

Non-GMO

Vegan

Isotonic
Directions for Use

Pour one small capful (3.3g) of Isotonix Advanced B-Complex into a cup.

Mix 60 ml of water for each capful and mix.

Enjoy once a day. For maximum absorption take on an empty stomach.
Key Ingredients & Benefits

Vitamin B6 (P5P)
Contributes to normal psychological functions
the reduction of tiredness and fatigue
and normal energy metabolism

Folate (Vitamin B9)
Contributes to healthy blood cell formation and division,
immune system functions, homocysteine metabolism
and amino acid synthesis

Niacinamide (Vitamin B3)
Contributes to nervous system functions
and the maintenance of normal skin
and mucous membranes

Vitamin B12
Essential for energy production
Contributes to normal red blood cell formation
Isotonix Delivery System

:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What is the source of the vitamin B12 in our Isotonix Advanced B-Complex?
Vitamin B12 is a byproduct of bacterial fermentation—not synthesized by plants or animals. While it's commonly found in animal-based foods like eggs and meat, this formula sources B12 through a clean, fermentation-based process, making it completely suitable for vegetarians. Since plant-based diets typically lack sufficient B12, health authorities recommend that vegetarians and vegans supplement.
Why are B-vitamins so important in the aging process?
The ability to absorb B-vitamins naturally decreases with age, and various indicators of cognitive impairment are associated with reduced B-vitamin levels. The elderly in general suffer from a reduction in sense of taste and thus appetite and may use many acid reducing medicines that predispose them to B12 deficiency. Vitamin B12 is an incredibly difficult nutrient to assimilate and digest as well as one of the most important vitamins for a broad range of bodily functions including optimal functioning of the nervous system, normal DNA and RNA synthesis, optimal energy production and healthy blood integrity.
Why should I take Isotonix Advanced B-Complex?
The ability to absorb B-vitamins naturally decreases with age, and various indicators of cognitive impairment are associated with reduced B-vitamin levels. The elderly in general suffer from a reduction in sense of taste and thus appetite and may use many acid reducing medicines that predispose them to B12 deficiency. Vitamin B12 is an incredibly difficult nutrient to assimilate and digest as well as one of the most important vitamins for a broad range of bodily functions including optimal functioning of the nervous system, normal DNA and RNA synthesis, optimal energy production and healthy blood integrity.
Why should I take Isotonix Advanced B-Complex?
Health experts estimate that one in five adults is deficient in one of the B-vitamins. Absorption of vitamin B12 is a complex process, which can lead to B12 deficiency. Keep in mind that even in a healthy person’s gastrointestinal tract, there are always other proteins and vitamins competing for absorption alongside vitamin B12, which is so large and complex that it very often must struggle for entrance into the bloodstream.
Is it toxic to take too much vitamin B12?
Studies have found no confirmed reports of toxic side effects from heightened dosages of vitamin B12. However, you should only take Isotonix Advanced B-Complex as directed on the bottle.
Scientific Research
- Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
- Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
- Bhagavan, H. N., et al. The effect of pyridoxine hydrochloride on blood serotonin and pyridoxal phosphate contents in hyperactive children. Pediatrics. 55(3):437-441, 1975.
- Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
- Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
- Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
- combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
- Coppen, A., et al. Plasma folate and affective morbidity during long-term lithium therapy. Br J Psychiatry. 141:87-89, 1982.
- Cummings, P. M., et al. Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 36:758-765, 2000.
- Dharmarajan, T. S., et al. Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics. 58(3):30-34, 2003.
- Doshi, S. N., et al. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation. 105(1):22-26, 2002.
- Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
- Friso, S., et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr. 79(6):992-998, 2004.
- Grant, J. E., et al. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 96(4):383-386, 1996.
- Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
- Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 92(4):183-185, 1999.
- Heseker, H., et al. Psychological disorders as early symptoms of a mild-to-moderate vitamin deficiency. Ann N Y Acad Sci. 669:352-357, 1992.
- Jacobson, W., et al. Serum folate and chronic fatigue syndrome. Neurology. 43:2645-2647, 1993.
- Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4(4):249-265, 1999.
- Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise., 17(Supplement):287, 1985.
- Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
- Quadri, P., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr. 80(1):114-122, 2004.
- Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
- Van den Berg M., et al. Combined vitamin B-6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia. Journal Vascular Surgery. 20(6):933-940, 1994.
- van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
- Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
- Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
- Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review. 5(2):93-108, 2000.
- Woo, K. S., et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. American Journal of Medicine. 112(7):535-539, 2002.
Reviews
Customer Rating
4.6 out of 5 star rating.
(77 reviews)
would recommend this product.
- Newest
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Customer Images
My husband and I both love this product! We have both noticed our energy pick up significantly and he even comes home from work and is in a good mood. I find if I have a slump at mid day - to take a dose and breeze through until bedtime!
Response from Customer Service on 06/21/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Activated B Complex! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
Isotonix activated b-complex
by Linda TunuraB
Shop Consultant
on 05/24/2023
Yes, I give it 5 stars! . This is so needed in my daily nutrients. Thank you so ! !
Response from Customer Service on 05/25/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Activated B Complex! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
Improved focus
by KENRICK YEE SAMT
Shop Consultant
on 05/08/2023
Been taking this for a while as it keeps me more energetic and focus at work. Can't go a day without it.
Response from Customer Service on 05/11/2023
Dear Valued Customer,
Thank you for your positive feedback on the Isotonix™ B-Complex Plus Powder. We are glad that you are happy with our product.
Thank you.
Shop.com Team
Shoppers found this review helpful
LOVE THIS
by Anonymous
on 02/14/2023
As a vegan, this gives me the B12 I need!
Response from Customer Service on 02/14/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Activated B Complex! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
Shoppers found this review helpful
Can't do without this isotonix Bcomplex is great..
by RogerH
on 04/12/2022
BestI have taken with results.
Response from Customer Service on 04/12/2022
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Activated B Complex! We are happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
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