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Curcumin Extreme

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Single Bottle (30 Servings) Code: C13147

Taking proper care of your body as you age provides support for overall health. Curcumin Extreme™ provides patented Curcugreen™ † , broccoli seed extract and selenium, which work together to protect against oxidative stress and help...
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Benefits

  • Source of an antioxidant.
  • Source of an antioxidant for the maintenance of good health.
  • Provides an antioxidant that helps protect against oxidative stress.

See adjacent text for equivalent image description

Product Classifications

Gluten Free — The finished product contains no detectable gluten (<10ppm gluten)

Vegan — This product is made without any ingredients produced by or derived from animals

Quality Standards — GMP Operations and Standardized Ingredients

Checked For — Heavy metals, microbiological contaminants, allergens, residual solvents, potency, purity and identity

Details

Curcumin Extreme™ is a supplement that promotes numerous biological functions, including overall liver health and normal production of detoxification enzymes, helping to scavenge toxins in the body that can build up over time. Curcumin Extreme™ also promotes overall cell integrity, cognitive health, and maintenance of healthy glutathione levels. Glutathione is known as the master antioxidant in the human body that preserves and protects the liver, brain and other body tissues from free radicals. Furthermore, glutathione supports two other powerful antioxidants, vitamins C and E.*

Curcumin Extreme™ features the patented and significantly researched ingredient, Curcugreen™. Scientists have long been aware of the wide array of health benefits from the Indian spice Curcuma longa (common name: turmeric), which is the source of the phytochemical curcumin. In general, most curcumins have poor bioavailability (poor absorption), often requiring high serving sizes or enhancers in order to promote better absorption. Unlike many curcumin products on the market, Curcumin Extreme™ with Curcugreen provides exceptional bioavailability so you can actively receive maximum benefits.

Curcugreen™ 
is safe and does not contain any synthetic enhancers.1 It also delivers a significant amount of bioactive curcumin into the blood and demonstrates high bioavailability. Unlike many of its competitors, Curcugreen™ is a turmeric extract, containing a proprietary blend of curcuminoids and turmeric oils.1 The AR tumerone± compound in turmeric supports the bio-activity and absorption of the curcumin in Curcugreen™ without harming the integrity of the product.1

Curcumin Extreme™ also includes broccoli seed extract, a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of phase II liver detoxification enzymes including glutathione synthase, heme-oxygenase and catalase. Glutathione is considered the master antioxidant in the human body that serves to protect the brain and other body tissues from free radicals.

This product is free of these common allergens: gluten, soy, wheat and dairy.

Curcugreen™ is a trademark of Arjuna Natural Ltd. CurcuGreen™ was previously sold under the trademark BCM-95®/Bio-curcumax®/Bio-curcumin®.

±AR-tumerone is a major bioactive compound and the most powerful element of Curcuma longa.

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Ingredients

Curcugreen (Curcuma longa rhizome standardized to 88% curcuminoids and essential oils): 400 mg

Curcugreen™ is a branded curcumin ingredient made from turmeric extract which contains a proprietary blend of curcuminoids and turmeric oils. Though most curcumins have poor bioavailability, Curcugreen offers a high level of oral bioavailability in order for the body to reap the full spectrum of health benefits curcumin can provide.*

Curcumin is the main active ingredient in turmeric. Turmeric, used historically for health and cosmetic purposes, as well as a fabric dye and a culinary spice, comes from the Curcuma longa plant. Curcumin, in and of itself, has also been used to support health and for cooking. Presently the science community has shown an interest in learning more about curcumin and its possible benefits.* 

In studies, curcumin has shown evidence of being able to support immune, cognitive and liver health. It also appears to boast antioxidant properties and to protect the body from free radicals. Curcumin has been shown to support the production of enzymes for glutathione and its synthesis, as well as metabolism.2 Glutathione is produced naturally by the body and has antioxidant properties.*

In addition to its immune-supporting activity, curcumin has been shown to support normal Cyclooxygenase-2 (COX-2) and NF-kappaB (NF-kB) levels in the body through multiple mechanisms. NF-kB is a transcription factor, meaning that it functions to support the normal formation of a specific protein encoded by a gene – specifically the COX-2 gene.3*

Curcumin has been shown to help maintain neurological health and cognitive function. Curcumin may help by promoting healthy levels of amyloid-β protein (a protein fragment) in the brain. In recent studies, researchers have linked normal levels of amyloid-β protein to neurological and cognitive health, such as memory and mood. Another neuroprotective property of curcumin is its ability to promote normal levels of glutathione, superoxide dismutase (SOD) and catalase in the brain, which can help maintain the health of neurological tissues. SOD and catalase are enzymes that protect cells.*

Curcumin supports liver health and its functions. In studies, curcumin has shown to support the normal production of phase II detoxification enzymes in the liver. These detoxification enzymes promote the body’s natural defense systems and function as powerful indirect antioxidants, helping to neutralize harmful heavy metals, toxins and pollutants. For example, curcumin’s support of glutathione synthesis supports the detoxification function of glutathione transferase. Curcumin also promotes normal liver tissue. *

Curcugreen™ is a trademark of Arjuna Natural Ltd.

Broccoli Seed Extract (Glucosinolates): 245 mg

The health benefits and protective properties of broccoli and other cruciferous vegetables are well known and supported. Broccoli seed extract is a powerful source of sulforaphane. Sulforaphane supports the normal production of phase II detoxification enzymes, which promotes the body’s normal metabolism of chemicals and toxins. Sulforaphane also promotes the body’s natural defense systems and functions as a powerful indirect antioxidant – meaning it supports the ability of antioxidants that directly protect the body from oxidative stress.*

Sulforaphane works to maintain healthy levels of glutathione. Known by scientists as the master antioxidant, glutathione is one of the body’s key antioxidants, and serves as a protector from free radicals and other toxins. Glutathione is also capable of recycling other antioxidants and supporting immune health and healthy detoxification among other things.*

Indole-3-carbinol (I3C), a product of glucosinolates present in cruciferous vegetables, is known to support normal mast cell genesis. One important health benefit of I3C is its ability to induce apoptosis and suppress free-radical production. Numerous studies have indicated that I3C also has strong hepato-protective activity.*

Selenium (L-Selenomethionine): 100 mcg

L-Selenomethionine provides a bioavailable form of selenium. It uses the same active transport mechanism as for methionine, one of the nine essential amino acids that can only be obtained from the diet, and this increases the efficiency of absorption of selenomethionine over inorganic forms of selenium. Selenium is an essential mineral that is important for the proper functioning of many body processes. This essential element is a required component of the selenoproteins, which includes those that are needed to convert thyroid hormones from the inactive to the active form, and several important antioxidants. As an antioxidant, it helps control free radicals and reduce oxidative stress. Selenium is a required cofactor for glutathione peroxidase (neutralizes hydrogen peroxide) and studies show it may help to increase levels of this antioxidant enzyme. In addition to promoting healthy levels of glutathione, selenium also promotes neurological health and a healthy immune system.*

FAQ

What is Curcumin?
Curcumin is present in the spice turmeric, frequently used in Indian food. Its chemical makeup is responsible for the yellow colouring of turmeric, and is often used specifically to give color to foods. However, it may serve a more important purpose to humans.

Are any side effects associated with Curcumin Extreme™?
Side effects are uncommon and are generally limited to mild stomach distress.

What are the potential advantages of taking curcumin?
Curcumin has been shown to be a powerful antioxidant. It can also promote free radical protection and maintain good health.

Are there any warnings associated with taking Curcumin Extreme™?
If you are currently using Warfarin (Coumadin) or other antiplatelet / anticoagulant medications, you should not take this product. If you are taking any prescription medications or have an ongoing medical condition, you should consult your healthcare practitioner before using this product. Consult a healthcare practitioner prior to use if you have gallstones or a bile duct obstruction, or stomach ulcers or excess stomach acid. Women who are pregnant or breastfeeding should not take this product. Consult a healthcare practitioner if symptoms persist or worsen.

What is the recommended daily serving for Curcumin Extreme™?
Take 1capsule daily, with or without a meal. 

Can men and women take this product?
Yes. However, women who are pregnant or nursing should not take this product.

Does Curcumin Extreme™ contain any allergens?
Yes, Curcumin Extreme™ contains soy. Anyone who is allergic to soy and soy-based products should not take this product.

Science

  • Araujo, C. and Leon, L. Biological activities of Curcuma longa L. Memorias do Instituto Oswaldo Cruz. 96(5): 723-728, 2001.
  • Bhattacharyya, S., et al. Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction. Journal of Biological Chemistry. 282(22): 15954-15964.
  • Biswas, S., et al. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxidants and Redox Signaling. 7(1-2): 32-41, 2005.
  • Biswas, S., et al. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxidants and Redox Signaling. 7(1-2): 32-41, 2005.
  • Cheng, Y., et al. Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells. Chinese Medical Journal. 120(9): 794-801, 2007.
  • Churchill, M., et al. Inhibition of intestinal tumors by curcumin is associated with changes in the intestinal immune cell profile. Journal of Surgical Research. 89(2): 169-175, 2000.
  • Dairam, A., et al. Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. Journal of Agricultural and Food Chemistry. 55(3): 1039-1044, 2007.
  • Dickinson, D., et al. Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression. FASEB. 17(3): 473-475, 2003.
  • Farombi, E., et al. Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food and Chemical Toxicology. 46(4): 1279-1287, 2008.
  • Funk, J., et al. Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. Journal of Natural Products. 69(3): 351-355, 2006.
  • Garcia-Alloza, M., et al. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. Journal of Neurochemistry. 102(4): 1095-1104, 2007.
  • Howells, L., et al. Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines. International Journal of Cancer. 121(1): 175-183, 2007.
  • Jagetia, G. and Aggarwal, B. "Spicing up" of the immune system by curcumin. Journal of Clinical Immunology. 27(1): 19-35, 2007.
  • Johnson, J., et al. Curcumin for chemoprevention of colon cancer. Cancer Letters. 255(2): 170-181, 2007.
  • Juge, N., et al. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cellular and Molecular Life Sciences. 64(9): 1105-1127, 2007.
  • Kaur, G., et al. Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents. Clinical and Experimental Immunology. 145(2): 313-321, 2006.
  • Kim, G., et al. Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets. Journal of Immunology. 174(12): 8116-8124, 2005.
  • Kurup, V., et al. Immune response modulation by curcumin in a latex allergy model. Clinical and Molecular Allergy. 5: 1, 2007.
  • Lim, G., et al. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Journal of Neuroscience. 21(21): 8370-8377, 2001.
  • Lin, J. Molecular targets of curcumin. Advances in Experimental Medicine and Biology. 595: 227-243, 2007.
  • Magalska, A., et al. Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells. Acta Biochimica Polonica. 53(3): 531-538, 2006.
  • Maheshwari, R., et al. Multiple biological activities of curcumin: a short review. Life Sciences. 78(18): 2081-2087, 2006.
  • Mathuria, N. and Verma, R. Ameliorative effect of curcumin on aflatoxin-induced toxicity in DNA, RNA and protein in liver and kidney of mice. Acta Poloniae Pharmaceutica. 64(6): 497-502, 2007.
  • Curcuma longa (turmeric). Alternative Medicine Review. 6(suppl): S62-S66, 2001.
  • Naik, R., et al. Protection of liver cells from ethanol cytotoxicity by curcumin in liver slice culture in vitro. Journal of Ethnopharmacology. 95(1): 31-37, 2004.
  • Nanji, A., et al. Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. American Journal of Physiology. 284(2): G321-G327, 2003.
  • Ng, T., et al. Curry consumption and cognitive function in the elderly. American Journal of Epidemiology. 164(9): 898-906, 2006.
  • Nishinaka, T., et al. Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element. Toxicology Letters. 170(3): 238-247, 2007.
  • O’Connell, M. and Rushworth, S. Curcumin: potential for hepatic fibrosis therapy? British Journal of Pharmacology. 153(3): 403-405, 2007.
  • Osawa, T. Nephroprotective and hepatoprotective effects of curcuminoids. Advances in Experimental Medicine and Biology. 595: 407-423, 2007.
  • Pal, S., et al. Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor-bearing mice by curcumin. Cancer Detection and Prevention. 29(5): 470-478, 2005.
  • Pari, L. and Amali, D. Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats. Journal of Pharmacy and Pharmaceutical Sciences. 8(1): 115-123, 2005.
  • Perkins, S., et al. Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis. Cancer Epidemiology, Biomarkers, and Prevention. 11(6): 535-540, 2002.
  • Rushworth, S., et al. Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. Biochemical and Biophysical Research Communications. 341(4): 1007-1016, 2006.
  • Salvioli, S., et al. Curcumin in cell death processes: A challenge for CAM of age-related pathologies. Evidence-based Complementary and Alternative Medicine. 4(2): 181-190, 2007.
  • Scapagnini, G., et al. Curcumin activates defensive genes and protects neurons against oxidative stress. Antioxidants and Redox Signaling. 8(3-4): 395-403, 2006.
  • Shen, G., et al. Modulation of nuclear factor E2-related factor 2-mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin. Molecular and Cancer Therapeutics. 5(1): 39-51, 2006.
  • Shen, S., et al. Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes. World Journal of Gastroenterology. 13(13): 1953-1961, 2007.
  • Shishodia, S., et al. Curcumin: getting back to the roots. Annals of the New York Academy of Sciences. 1056: 206-217, 2005.
  • Shu, J., et al. The study of therapeutic effects of curcumin on hepatic fibrosis and variation of correlated cytokine. Journal of Chinese Medicinal Materials. 30(11): 1421-1425, 2007.
  • Shu, J., et al. Therapeutic effects of curcumin treatment on hepatic fibrosis. Chinese Journal of Hepatology. 15(10): 753-757, 2007.
  • Shukla, P., et al. Protective effect of curcumin against lead neurotoxicity in rat. Human and Experimental Toxicology. 22(12): 653-658, 2003.
  • Srinivasan, M., et al. Protective effect of curcumin on gamma-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes. Mutation Research. 611(1-2): 96-103, 2006.
  • Thangapazham, R., et al. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS Journal. 8(3): E443-E449, 2006.
  • Thangapazham, R., et al. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS Journal. 8(3): E443-E449, 2006.
  • Wei, Q., et al. Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by curcumin and its analogues. Biochimica et Biophysica Acta. 1760(1): 70-77, 2006.
  • Wu, A., et al. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. 197(2): 309-317, 2006.
  • Xu, Y., et al. Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB. Brain Research. 1122(1): 56-64, 2006.
  • Yadav, V., et al. Immunomodulatory effects of curcumin. Immunopharmacology and Immunotoxicology. 27(3): 485-497, 2005.
  • Yang, F., et al. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. Journal of Biological Chemistry. 280(7): 5892-5901, 2005.
  • Ye, S., et al. Effect of curcumin on the induction of glutathione S-transferases and NADP(H):quinone oxidoreductase and its possible mechanism of action. Acta Pharmaceutica Sinica. 42(4): 376-380, 2007.
  • Zhang, L., et al. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients. Journal of Alzheimer’s Disease. 10(1): 1-7, 2006.
  • Zheng, S. and Chen, A. Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor. American Journal of Physiology. 290(5): G883-G893, 2006.
  • Zheng, S. and Chen, A. Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells. American Journal of Physiology. 292(1): G113-G123, 2007.
  • Zheng, S., et al. De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation. Free Radical Biology and Medicine. 43(3): 444-453, 2007.

Reviews

Customer Rating

4.9 out of 5 star rating.

(12 reviews)

Break down of ratings:
(11) 5 star ratings.
or, 92% of total reviews.
(1) 4 star ratings.
or, 8% of total reviews.
(0) 3 star ratings.
or, 0% of total reviews.
(0) 2 star ratings.
or, 0% of total reviews.
(0) 1 star ratings.
or, 0% of total reviews.
100%

would recommend this product.

Write a Review

Great product

5 out of 5 star rating.

by Anonymous

on 12/13/2022

I would like to recommend the product to the friends and family

Response from Customer Service on 12/13/2022

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Curcumin Extreme™! We are so happy to hear you are pleased with the product!

Thank you again!
The Product Information Team

Detoxing your liver

5 out of 5 star rating.

by Kong

Shop Consultant

Shop Consultant is an independent distributor of this product.

on 07/15/2022

This is a good product for those heavy drinker. It help to detox your liver. I loved this product. 😉

Response from Customer Service on 07/21/2022

Dear Valued Customer,

Thank you for taking the time to leave your thoughts on the Curcumin Extreme™. We are happy to hear you are pleased with the product.

Thank you again! Market Singapore Product Team

Curcumin

5 out of 5 star rating.

by AllisonC

on 09/04/2020

I was having a pain in my shoulder and the doc wanted to give me an injection however; I used this product and I no longer have the pain. This was the right move on my part.

Response from Customer Service on 09/04/2020

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Curcumin Extreme! We are happy to hear you are pleased with the product.

Thank you again!
The Product Information Team

What a Relief!

5 out of 5 star rating.

by FlorenceL

Shop Consultant

Shop Consultant is an independent distributor of this product.

on 09/04/2020

I was suffering from knee pains about 6 months ago and my sister recommended me to try Curcumin. I did and I noticed the pain lessened after 3 days and I am free from knee pain since. I have been taking this product daily ever since!

Response from Customer Service on 09/06/2020

Dear Valued Customer,

Thank you for taking the time to share your thoughts on the Curcumin Extreme! We are happy to hear you are pleased with the product.

Thank you again!
The Product Information Team

Can't Live Without Curcumin Extreme

5 out of 5 star rating.

by DawnK

on 03/26/2020

This product is fantastic! I can't live without this important supplement. Do yourself a favor and get yourself some and take it every single day. Our bodies need this supplement especially as we get older! Thank you Market America for your wonderful products that actually work and don't contain all the extras we don't need and that are more bio-available than anything else on the market! I'm a Market America lifer!!!

Response from Customer Service on 03/26/2020

Dear Valued Customer,

Thank you for taking the time to leave your thoughts on the Curcumin Extreme™! We are happy to hear you are pleased with the product.

Thank you again!
The Product Information Team

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